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13 Sleeve gastrectomy involved a gastric-volume reduction of 75 to 80% by resecting the stomach alongside a 30-French endoscope beginning 3 cm from the pylorus and ending at the angle of His (Fig. Bertakis, Peter Franks. CrossRef 165 M. There was a marked increase in high-density lipoprotein (HDL) cholesterol and a significant decrease in the high-sensitivity CRP level after the two surgical procedures, as compared with medical therapy alone. Portenier. 11 The study was conducted in eight European countries: Denmark, the Netherlands, the United Kingdom, Greece (Crete), Germany, Spain, Bulgaria, and the Czech Republic. CrossRef 176 Sayeed Ikramuddin. CrossRef 163 Magnus Sundbom. Kashyap. Davidson, Steven C. C. Surgery for Obesity and Related Diseases 12:1, 119-126. Bariatric Surgical Practice and Patient Care 10:2, 45-48. (2016) Bariatric Surgery. George M. Cohen. (2015) Weight loss surgery and cardiovascular risk and mortality in patients with type 2 diabetes. Reviews in Endocrine and Metabolic Disorders 17:2, 195-207. Hannah, Stephen A. Wolfe, Donna H. (2016) Orthostatic intolerance and autonomic dysfunction following bariatric surgery: A retrospective study and review of the literature. The first author wrote the first draft of the manuscript and made the decision to submit the manuscript for publication. Scott Melvin, Diego R. Collazo-Clavell, Manpreet S. All authors had full and independent access to all the data and vouch for the integrity and the accuracy of the analysis and its fidelity to the protocol. Berends. Surgery for Obesity and Related Diseases 12:1, 20-22. Treatment of obesity: bariatric surgery. Surgery for Obesity and Related Diseases 12:3, e25-e26. Inge. Tahrani. Joyce, Cormac G. Kelly, Thomas H. CrossRef 179 Neil G Docherty, Carel W Le Roux. American Journal of Obstetrics and Gynecology 213:3, 350. Study End Points The primary end point was the proportion of patients with a glycated hemoglobin level of 6% or less (with or without diabetes medications) 12 months after randomization. David Mosinski, John P. (2016) Hospital variation in perioperative complications for laparoscopic sleeve gastrectomy in Michigan. 2015. (2016) Predictive factors of biliary complications after bariatric surgery. Foster-Schubert, David R. (2016) Bariatric surgery and remission of type 2 diabetes mellitus. Turgeon. (2015) Advances in the Science, Treatment, and Prevention of the Disease of Obesity: Reflections From a. Home, W. Graham, Joshua Richman, Manasi Kakade, Richard Stahl, Jayleen Grams. Ahmed, Rongrong Zhang, Zeynep Colpan, Jan Hedenbro. CrossRef 139 R Lupoli, M N D Di Minno, C Guidone, C Cefalo, B Capaldo, G Riccardi, G Mingrone. Romney, Ricardo Cohen, Francesco Rubino, Philip Schauer, Pierre Cremieux. Gastric bypass vs. Russell-Jones, K. Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes. Billington, Scott A. (2016) Clinical Outcomes of Metabolic Surgery: Efficacy of Glycemic Control, Weight Loss, and Remission of Diabetes. Needleman, Sabrena F. Categorical variables are summarized with the use of frequencies. (2015) A Pilot Study to Compare Meal-Triggered Gastric Electrical Stimulation and Insulin Treatment in Chinese Obese Type 2 Diabetes. CrossRef 293 Cristian Ricci, Maddalena Gaeta, Emanuele Rausa, Emanuele Asti, Francesco Bandera, Luigi Bonavina. Mahdy, A. Although lipoprotein and blood-pressure levels were similar in all three study groups at 12 months, improvements in the surgical groups allowed reduction or elimination of concomitant medications in many patients. (2016) Seven Years of Mini-Gastric Bypass in Type II Diabetes Patients with a Body Mass Index Obesity Surgery 26:7, 1457-1462. CrossRef 238 Aparna Govil Bhasker, Carlyne Remedios, Payal Batra, Amit Sood, Shehla Shaikh, Muffazal Lakdawala. Cripps. Davern. Surgery for Obesity and Related Diseases 11:4, 798-805. Armour Forse. Surgery for Obesity and Related Diseases 12:3, 468-495. (2016) Pancreas transplantation in unconventional recipients. (2016) Duodenal-jejunal bypass surgery induces hepatic lipidomic alterations associated with ameliorated hepatic steatosis in mice. CrossRef 18 Bark Betzel, Jens Homan, Edo O. CrossRef 250 J. The durability and long-term safety profile of these results remain uncertain, but the protocol specifies further 4-year follow-up of all patients, which should allow additional assessment of long-term efficacy and safety results to guide patient counseling regarding specific bariatric procedures for the treatment of type 2 diabetes. CrossRef 158 Eng-Hong Pok, Wei-Jei Lee, Kong-Han Ser, Jung-Chien Chen, Shu-Chun Chen, Ju-Juin Tsou, Kin-Fah Chin. Kenngott, Thilo Schulte, Gabriella Clemens, Ulrike Zech, Markus W. (2016) IV Acetaminophen Results in Lower Hospital Costs and Emergency Room Visits Following Bariatric Surgery: a Double-Blind, Prospective, Randomized Trial in a Single Accredited Bariatric Center. The overall study leaders, together with the principal investigator at each study center, designed the study. (2015) Long-term Results on Weight Loss and Diabetes Remission after Laparoscopic Sleeve Gastrectomy for A Morbidly Obese Chinese Population. W. Shimizu, E. Carey, P. (2015) Endoluminal bariatric and metabolic interventions. We assessed body weight, waist and hip circumference, blood pressure, and levels of glycated hemoglobin and fasting plasma glucose at baseline and at months 3, 6, 9, and 12. CrossRef 181 Alper Celik, Muharrem Asci, Bahri Onur Celik, Surendra Ugale. (2016) Hypovitaminosis D in bariatric surgery: A systematic review of observational studies. Cetta, F. Media in This Article Figure 1 Changes in Measures of Diabetes Control from Baseline. This randomized, controlled, single-center study, called the Surgical Treatment and Medications Potentially Eradicate Diabetes Efficiently (STAMPEDE) trial, was designed to compare intensive medical therapy with surgical treatment (gastric bypass or sleeve gastrectomy) as a means of improving glycemic control in obese patients with type 2 diabetes. CrossRef 266 Yong Joon Kim, Du Ri Seo, Myung Jin Kim, Sung Jin Lee, Kyung Yul Hur, Kyung Seek Choi. Mirensky. The goal of medical management was modification of diabetes medications until the patient reached the therapeutic goal of a glycated hemoglobin level of 6. Coen, Bret H. Cheema. A systematic review with meta-analysis of randomised, sham controlled trials. Bischoff, Yves Boirie, Tommy Cederholm, Michael Chourdakis, Cristina Cuerda, Nathalie M. Annual Review of Food Science and Technology 7:1, 313-333. (2016) Gastric bypass surgery vs intensive lifestyle and medical intervention for type 2 diabetes: the CROSSROADS randomised controlled trial. (2016) Effects of bariatric surgery on markers of subclinical atherosclerosis and endothelial function: a meta-analysis of literature studies. Burgess, Nana Gletsu-Miller. CrossRef 220 James Charles Hopkins, Richard Welbourn. CrossRef 180 Lars Fischer, Anna-Laura Wekerle, Thomas Bruckner, Inga Wegener, Markus K. CrossRef 192 Shirley Yuk-Wah Liu, Simon Kin-Hung Wong, Candice Chuen-Hing Lam, Man Yee Yung, Alice Pik-Shan Kong, Enders Kwok-Wai Ng. Surgery for Obesity and Related Diseases 12:8, 1449-1456. (2016) The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions. (2015) Weight Loss and the Prevention and Treatment of Type 2 Diabetes Using Lifestyle Therapy, Pharmacotherapy, and Bariatric Surgery: Mechanisms of Action. Inge, Rohit Kohli. (2015) Predictors of Remission of Diabetes Mellitus in Severely Obese Individuals Undergoing Bariatric Surgery. (2016) Laparoscopic sleeve gastrectomy in Asia: Long term outcome and revisional surgery. Batterham. M. Abu Dayyeh, Andres Acosta, Michael Camilleri, Manpreet S. CrossRef 149 Xiaoling Song, Mark Kestin, Yvonne Schwarz, Pamela Yang, Xiaojun Hu, Johanna W. (2016) Efficacy of single anastomosis sleeve ileal (SASI) bypass for type-2 diabetic morbid obese patients: Gastric bipartition, a novel metabolic surgery procedure: A retrospective cohort study. Harrison. CrossRef 98 Tamar L. Owens, Sanjay Purkayastha, Valeria Iodice, Christopher J. Smith, Jun Lu, Richard Babor, Michael Booth, Grant Beban, J. Boido, V. Schauer, Matthew D. CrossRef 186 Dimitri J Pournaras, Richard Welbourn. P. DiMarchi. Sleeve Gastrectomy: Balancing the Risks of Surgery with the Benefits of Weight Loss. Standards of medical care in diabetes -- 2011. ). (2015) Biologic Responses to Weight Loss and Weight Regain: Report From an American Diabetes Association Research Symposium. Birkenfeld, Stefan Bornstein, Melania Manco, Geltrude Mingrone. Setchell, Thomas H. Abstract Background Observational studies have shown improvement in patients with type 2 diabetes mellitus after bariatric surgery. CrossRef 104 J. (2016) Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress. Martinez. e1. Mathias. G. Cummings. CrossRef 107 Yan Mei Goh, Zaher Toumi, Ravindra S. Gastric bypass consisted of the creation of a 15-to-20-ml gastric pouch, a 150-cm Roux limb, and a 50-cm biliopancreatic limb (Fig. CrossRef 265 Sigal Fishman, Mati Shnell, Nathan Gluck, Shmuel Meirsdorf, Subhi Abu-Abeid, Erwin Santo. Wahab, Marcel J. (2016) Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations. Endocrinology and Metabolism Clinics of North America 45:3, 657-665. Zimmet, K. C. Specific effects of biliopancreatic diversion on the major components of metabolic syndrome: a long-term follow-up study. M. Endocrinology and Metabolism Clinics of North America 45:3, 667-676. Alberti. CrossRef 2 Hidekazu Yamada. Jensen, Adrian Vella, Leaque Ahmed, Kumar Belani, Joyce L. (2015) Referring survivors of endometrial cancer and complex atypical hyperplasia to bariatric specialists: a prospective cohort study. -A. CrossRef 221 Parveen Bhatia, Vivek Bindal, Usha Dudeja. 0% or less or became intolerant to the medical treatment (Fig. (2015) CLINICAL COURSE OF DIABETIC RETINOPATHY IN KOREAN TYPE 2 DIABETES AFTER BARIATRIC SURGERY. Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the Look AHEAD trial. Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. L. Despite these limitations, we conclude that bariatric surgery represents a potentially useful strategy for management of uncontrolled diabetes, since it has been shown to eliminate the need for diabetes medications in some patients and to markedly reduce the need for drug treatment in others. CrossRef 212 Oleg Borisenko, Daniel Adam, Peter Funch-Jensen, Ahmed R. CrossRef 152 Darleen Sandoval. (2016) Ileal Transposition Decreases Plasma Lipopolysaccharide Levels in Association with Increased L Cell Secretion in Non-obese Non-diabetic Rats. Sayed, Nicole A. CrossRef 240 Alper Celik, Surendra Ugale, Hasan Ofluoglu, Muharrem Asci, Bahri Onur Celik, Erol Vural, Mustafa Aydin. Surgery for Obesity and Related Diseases 11:6, 1273-1280. Pai, P. Kashyap. CrossRef 8 Sidra Azim, Sangeeta R. Malin, Sangeeta R. Silva, G. 2017. Redler, N. Billing, P. CrossRef 93 Sohaib Khan, Kathryn Rock, Arunkumar Baskara, Weikai Qu, Munier Nazzal, Jorge Ortiz. (2015) Sleeve gastrectomy as a uric acid lowering therapy in morbid obesity. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Surgery for Obesity and Related Diseases 12:7, 1337-1341. Small, R. Castro-Perez, Xiaolan Shen, Yonghua Zhu, Haiying Liu, Ying Qian, Stephen Previs, Andrew D. CrossRef 25 Peter Vasas, Waleed Al-Khyatt, Iskandar Idris, Paul C. CrossRef 42 George Tharakan, Rebecca Scott, Olivia Szepietowski, Alexander D. Lombardi, A. sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. (2016) Fibroblast growth factor 21 correlates with weight loss after vertical sleeve gastrectomy in adolescents. H. CrossRef 35 Ricardo Zorron, Alcides Branco, Jose Sampaio, Claudia Bothe, Tido Junghans, Gyurdzhan Rasim, Johann Pratschke, Safak Guel-Klein. CrossRef 271 A. (2016) Update on Adolescent Bariatric Surgery. Clinical Gastroenterology and Hepatology 15:1, 37-43. CrossRef 310 S. Rates of hyperinsulinemia and the HOMA-IR index improved markedly after each of the two surgical procedures, as compared with medical therapy alone. In our study, results were generally similar in the two surgical groups although somewhat more favorable in the gastric-bypass group. CrossRef 185 Alper Celik, Surendra Ugale, Hasan Ofluoglu, Erol Vural, Eylem Cagiltay, Huseyin Cat, Muharrem Asci, Bahri Onur Celik. (2015) Iron Nutrition following Bariatric Surgery. Horn, Wendy Scinta, Craig Primack. Rogers. (2016) Receptivity to Bariatric Surgery in Qualified Patients. CrossRef 143 Konstantinos Albanopoulos, Dimitrios Tsamis, Maria Natoudi, Leonidas Alevizos, Georgios Zografos, Emmanouil Leandros. CrossRef 73 Benoit Navez, Theodoros Thomopoulos, Irina Stefanescu, Laurent Coubeau. Surgery for Obesity and Related Diseases 11:2, 308-312. Surgery for Obesity and Related Diseases 12:9, 1706-1710. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. CrossRef 31 Julietta Chang, Ricard Corcelles, Mena Boules, Mohammad H. R. Mahawar, Chetan Parmar, William R. Cummings. Billeter, Pascal Probst, Lars Fischer, Jonas Senft, Hannes G. (2015) Roux-en-Y gastric bypass is associated with an increased exposure to ionizing radiation. CrossRef 56 Gabriella Segal-Lieberman, Pesach Segal, Dror Dicker. CrossRef 129 Maher El Chaar, Jill Stoltzfus, Leonardo Claros, Tara Wasylik. (2015) Association of Race and Socioeconomic Status with Outcomes Following Laparoscopic Roux-en-Y Gastric Bypass. Frans Smulders, Guido H. Cohen, Scott Shikora, Tarissa Petry, Pedro Paulo Caravatto, Carel W Le Roux. E. (2015) Preoperative Interventions for Patients Being Considered for Bariatric Surgery: Separating the Fact from Fiction. 11 From March 2007 through January 2011, we screened 218 patients at the Cleveland Clinic. Mundi. CrossRef 308 Xiaofang Jia, Hisao Naito, Kazuya Kitamori, Husna Yetti, Tamie Nakajima. CrossRef 43 Haoyong Yu, Lei Zhang, Yuqian Bao, Pin Zhang, Yinfang Tu, Jianzhong Di, Xiaodong Han, Junfeng Han, Weiping Jia. Docherty. (2016) Changes in insulin sensitivity and secretion after sleeve gastrectomy. (2015) Bariatric Surgery: Three Surgical Techniques, Patient Care, Risks, and Outcomes. 3-MJ (800-kcal) low-calorie diet. CrossRef 204 Kab Choong Kim, Tae-ah Kim, Won Me Kang, Young Mi Kim, Soo Min Ahn. Surgery for Obesity and Related Diseases 11:2, 424-430. The role of sRAGE biomarker as predictor of satisfactory outcomes. CrossRef 188 Tomasz Rogula, Zhamak Khorgami, Martin Bazan, Cristina Mamolea, Pablo Acquafresca, Omar El-Shazly, Ali Aminian, Philip Schauer. Timothy Garvey. (2016) Pursuit of a perfect insulin. CrossRef 13 A C Carpentier. Bariatric Surgical Practice and Patient Care 10:1, 3-11. Most differences between the gastric-bypass group and the sleeve-gastrectomy group were not significant, although it should be noted that the study was not adequately powered to detect modest differences between these two surgical procedures. (2015) Acute Liver Failure Due to Acetaminophen Poisoning in Patients With Prior Weight Loss Surgery. (2015) Long-Term Effects of Bariatric Surgery on Type II Diabetes, Hypertension and Hyperlipidemia: A Meta-Analysis and Meta-Regression Study with 5-Year Follow-Up. CrossRef 141 Amin Mamoon Amin, Helen Wharton, Margaret Clarke, Ateeq Syed, Paul Dodson, Abd A. (2016) Increased post-operative cardiopulmonary fitness in gastric bypass patients is explained by weight loss. (2015) Surgical models of Roux-en-Y gastric bypass surgery and sleeve gastrectomy in rats and mice. CrossRef 264 Ze-Qiang Ren, Peng-Bo Zhang, Xiu-Zhong Zhang, Shou-Kun Chen, Hong Zhang, Dun-Tao Lv, Bu-Qiang Zhuang, Yu-Qing Wen, Hui-Hui Hu, Wei-Chao Ding, Chong Zhang. (2015) Effectiveness and Safety of Sleeve Gastrectomy, Gastric Bypass, and Adjustable Gastric Banding in Morbidly Obese Patients: a Multicenter, Retrospective, Matched Cohort Study. Surgery for Obesity and Related Diseases 12:6, 1256-1261. (2015) Pregnancy Risks Associated with Obesity. (2016) Alterations in hypothalamic gene expression following Roux-en-Y gastric bypass. 7 million participants. Statistical Analysis The sample-size estimate was based on the primary end point of the proportion of patients with a glycated hemoglobin level of 6% or less at 12 months. CrossRef 167 Hong Chang Tan, Matthew Zhen-Wei Tan, Kwang Wei Tham, Shanker Pasupathy, Alvin Kim Hock Eng, Sonali Ganguly, Oi Fah Lai, Alvin Choong Meng Ng. 2 (SAS Institute). K. CrossRef 162 Su-Ann Ding, Travis McKenzie, Ashley H. CrossRef 189 Yunmee Lho, Carel W. Vargas, Barham K. Patients were excluded if they had undergone previous bariatric surgery or other complex abdominal surgery or had poorly controlled medical or psychiatric disorders. There were no deaths, episodes of serious hypoglycemia requiring intervention, malnutrition, or excessive weight loss among the three groups. CrossRef 125 David Rometo, Mary Korytkowski. Z. le Roux, Neil G. (2016) Trends in bariatric surgery from 2008 to 2012. CrossRef 289 Peter Nau, George Molina, Aran Shima, Abujudeh Hani, Ozanan Meireles. R. Acute effects of gastric bypass versus gastric restrictive surgery on beta-cell function and insulinotropic hormones in severely obese patients with type 2 diabetes. Michener. Swain, E. CrossRef 178 Wayne B Jonas, Cindy Crawford, Luana Colloca, Ted J Kaptchuk, Bruce Moseley, Franklin G Miller, Levente Kriston, Klaus Linde, Karin Meissner. (2015) Predictors of Remission of T2DM and Metabolic Effects after Laparoscopic Roux-en-y Gastric Bypass in Obese Indian Diabetics—a 5-Year Study. Blakemore, Sanjay Purkayastha, Ahmed Ahmed, Harvinder Chahal, Tricia Tan. Use of Cardiovascular Medications Although levels of total and LDL cholesterol did not differ significantly among groups after 12 months, there was a significant reduction in the number of medications needed to treat hyperlipidemia in the two surgical groups ( Table 3 ). (2016) Towards a multidisciplinary approach to understand and manage obesity and related diseases. In addition, among patients undergoing surgery, cardiovascular risk factors improved, allowing reductions in lipid-lowering and antihypertensive therapies. (2016) Pediatric Nonalcoholic Fatty Liver Disease: the Rise of a Lethal Disease Among Mexican American Hispanic Children. Mutter. Pontiroli. (2016) Randomized trial of Roux-en-Y gastric bypass. Buniak, Louis J. Dumon. (2015) Bariatric surgery and diabetes: Implications of type 1 versus insulin-requiring type 2. CrossRef 137 Ricardo V. CrossRef 260 Gianluca Iacobellis, Chengyu Xu, Rafael E. Methods Study Protocol The study design, methods, and procedures have been described in detail previously. Zimmet, Stefano Del Prato, Linong Ji, Shaukat M. Hsia. CrossRef 94 Paul Z. Abstract Background Studies of weight-control diets that are high in protein or low in glycemic index have reached varied conclusions, probably owing to the fact that the studies had insufficient power. Kirwan. (2015) Long-Term Outcomes of Obesity Surgery and Implications for Health System Planning. 4 percentage points). Wimmelmann, L. (2015) Novel therapeutics for type 2 diabetes: insulin resistance. Complete study governance is outlined in the Supplementary Appendix. Brown, Robert V. Al wahedi, C. CrossRef 269 Xiaoming Shuai, Kaixiong Tao, Masayuki Mori, Tsugiyasu Kanda. Fox, Sherita Hill Golden, Cheryl Anderson, George A. CrossRef 87 Ricardo Cohen, Pedro Paulo Caravatto, Tarissa Zanata Petry. (2016) Medical Devices in the Treatment of Obesity. (2015) Clinical Management of Type 2 Diabetes Mellitus after Bariatric Surgery. Dela. The Progression of Non-alcoholic Fatty Liver Disease and Lifestyle Intervention in Older Adults. Kirwan. Accordingly, a significant improvement in type 2 diabetes (a reduction in glycated hemoglobin levels of 2. Wool. CrossRef 26 Haoyong Yu, Ronghui Du, Nina Zhang, Mingliang Zhang, Yinfang Tu, Lei Zhang, Yuqian Bao, Junfeng Han, Pin Zhang, Weiping Jia. Tahrani. Kashyap. CrossRef 122 Wei-Jei Lee, Abdullah Almulaifi, Keong Chong, Wei-Cheng Yao, Ju Juin Tsou, Kong-Han Ser, Yi-Chih Lee, Shu-Chun Chen, Jung-Chien Chen. Gahan. Jenkinson, Marco Anselmino, Ferruccio Santini, Marco Adamo, Rachel L. (2016) Managing dyslipidaemia in type 2 diabetes mellitus. Surgery for Obesity and Related Diseases 11:4, 805-807. R. Lebovitz, Enders Kwok-wai Ng, Juliana Chung-Ngor Chan. (2016) Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes. Diabetes in Native Populations and Underserved Communities in the USA. Study Oversight This investigator-initiated trial was sponsored by Ethicon Endo-Surgery, with support from LifeScan, the Cleveland Clinic, and the National Institutes of Health. Deitel. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Williams, Kristoffel R. C. Ceriani, F. e4. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2. Surgery for Obesity and Related Diseases 12:4, 803-804. Marescaux, D. (2015) Two-year outcomes on bone density and fracture incidence in patients with T2DM randomized to bariatric surgery versus intensive medical therapy. CrossRef 270 Mi Joung Kim, Jung Hyun Hwang, Hyun Ji Ko, Hye Bock Na, Jung Hee Kim. Mayer, Richard D. (2015) Gap Between Evidence and Patient Access: Policy Implications for Bariatric and Metabolic Surgery in the Treatment of Obesity and its Complications. CrossRef 160 Marco Barreca, Cristina Renzi, James Tankel, Joseph Shalhoub, Neel Sengupta. Altaf, A. (2015) An update on the role of bariatric surgery in diabetes management. Maximal improvements after bariatric surgery occurred quickly, often within 3 months, and were maintained throughout the 12-month follow-up period. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. (2015) Effect of Bariatric Surgery Versus Intensive Medical Management on Diabetic Ophthalmic Outcomes. Brethauer, Philip R. Awan, Sherif Awad, Javed Ahmed. M. Farland, Elizabeth S. CrossRef 239 Kemal Dogan, Ralph P. Patients were assessed for nutritional deficiencies within 12 months after surgery. CrossRef 187 Ignace M. Kaufman, J. (2016) Reproductive Outcomes Differ Following Roux-en-Y Gastric Bypass and Adjustable Gastric Band Compared with Those of an Obese Non-Surgical Group. Rose, Chad M. Groenen, Frits J. (2016) One-Anastomosis Jejunal Interposition with Gastric Remnant Resection (Branco-Zorron Switch) for Severe Recurrent Hyperinsulinemic Hypoglycemia after Gastric Bypass for Morbid Obesity. 2017. J. 9 percentage points) can occur after bariatric surgery in obese patients with advanced diabetes, although modest improvement is feasible with the use of intensive medical therapy alone (a reduction of 1. CrossRef 282 Simona Panunzi, Andrea De Gaetano, Annamaria Carnicelli, Geltrude Mingrone. The principal investigator at each study center collected the local data, which were entered into a data-registration system (EpiData) 12 and transferred to a central data hub. (2016) Insulin Resistance, Microbiota, and Fat Distribution Changes by a New Model of Vertical Sleeve Gastrectomy in Obese Rats. CrossRef 105 Michael A Nauck, Juris J Meier. Serrano, Yang Zhang, Lindsay Cumella, Emily Kintzer, Nicole Ng, Eduardo Sandoval, Jenny Choi, W. (2016) Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations. Date. C. (2016) The Use of Rat and Mouse Models in Bariatric Surgery Experiments. Alberti, Paul Z. Abumrad. Carlson. (2016) Comment on: Laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass lead to equal changes in body composition and energy metabolism 17 months postoperatively: a prospective randomized trial. Janssen, Jens Homan, Wendy Schijns, Bark Betzel, Edo O. (2016) Laparoscopic Sleeve Gastrectomy: Co-morbidity Profiles and Intermediate-Term Outcomes. (2015) Gastro-intestinal Quality of Life After Metabolic Surgery for the Treatment of Type 2 Diabetes Mellitus. Patterson, Ricardo Cohen, Samuel Klein. Brethauer, J. Daniel Guerron, Dana D. Schauer, Elizabeth Selvin, Dorothea K. CrossRef 70 Jianzhong Di, Hongwei Zhang, Haoyong Yu, Pin Zhang, Zhigang Wang, Weiping Jia. (2015) Vertical Sleeve Gastrectomy Restores Glucose Homeostasis in Apolipoprotein A-IV KO Mice. (2015) Cardiovascular, Renal and Overall Health Outcomes After Bariatric Surgery. Schauer, S. Velloso, Bruno Geloneze. (2015) A Case of Type 2 Diabetes Mellitus with Severe Insulin Resistance and Dumping Syndrome after Bariatric Surgery. A focus on surgical preoperative evaluation of the bariatric patient -- the Cleveland Clinic protocol and review of the literature. Janssen, Frits J. K. A. M. Brethauer, Julietta Chang, Manoel Galvao Neto, Jan Willem Greve. 2017. Neff, Ele Ferrannini, Carel W. Seeley, Tamara Darsow, Erika Gebel Berg, Steven R. Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding. (2015) Technical feasibility and safety profile of laparoscopic diverted sleeve gastrectomy with ileal transposition (DSIT). CrossRef 45 Giovanni Casella, Emanuele Soricelli, Domenico Giannotti, Maria Giulia Bernieri, Alfredo Genco, Nicola Basso, Adriano Redler. L. CrossRef 218 Shazli Azmi, Uazman Alam, Basil Ammori, Handrean Soran, Rayaz A Malik. Feher, D. Journal of Marital and Family Therapy 42:3, 495-508. Journal of Endocrinology, Metabolism and Diabetes of South Africa 20:3, 115-126. (2016) Iron-Deficiency Anemia After Laparoscopic Roux-en-Y Gastric Bypass in Chinese Obese Patients with Type 2 Diabetes: a 2-Year Follow-Up Study. (2016) Response to M. CrossRef 273 A Jerant, K D Bertakis, P Franks. The groups did not differ significantly with respect to diet-related adverse events. Cooper. Ochiai, R. Diabetes Mellitus in Developing Countries and Underserved Communities, 251-284. Surgery for Obesity and Related Diseases 11:5, 1044-1053. CrossRef 11 Mogens Fenger, Dorte Lindqvist Hansen, Dorte Worm, Lisbeth Hvolris, Viggo B. 2017. (2016) Roux-En-Y Gastric Bypass Vs. Postoperative Management of Obesity-Related Diseases. Alberti, Paul Z. Sleeve gastrectomy and type 2 diabetes mellitus: a systematic review.
(2016) Weight loss after bariatric surgery: a propensity score analysis. (2015) The small bowel microbiota. Billingto. George M. (2015) Clinical factors that predict remission of diabetes after different bariatric surgical procedures: interdisciplinary group of bariatric surgery of Verona (G. Surgery for Obesity and Related Diseases 12:3, 570-571. Surgery for Obesity and Related Diseases 12:6, 1178-1185. (2015) Effect of Duodenal-Jejunal Bypass Surgery on Glycemic Control in Type 2 Diabetes: A Randomized Controlled Trial. (2016) Racial differences in weight loss, hemoglobin A1C, and blood lipid profiles after Roux-en-Y gastric bypass surgery. Schauer. Aarts, Bark Betzel, Cees J. Carter, Mohamed Elkalaawy, Giorgia Querci, Silvia Magno, Anna Tamberi, Nicholas Finer, Alberic G. (2016) Perioperative Glycemic Management of Patients Undergoing Bariatric Surgery. Surgery for Obesity and Related Diseases 12:6, 1230-1235. CrossRef 99 Auryan Szalat, Ronen Durst, Eran Leitersdorf. (2015) Metabolic Outcomes of Laparoscopic Diverted Sleeve Gastrectomy with Ileal Transposition (DSIT) in Obese Type 2 Diabetic Patients. Methods We enrolled overweight adults from eight European countries who had lost at least 8% of their initial body weight with a 3. CrossRef 96 Rebekah Forbes, Danijela Gasevic, Emily M. (2015) Scheduled intravenous acetaminophen reduces postoperative narcotic analgesic demand and requirement after laparoscopic Roux-en-Y gastric bypass. (2016) Bariatric Surgery in Youth. Funk. V. (2015) Gut microorganisms as promising targets for the management of type 2 diabetes. CrossRef 255 Sean Manning, Andrea Pucci, Nicholas C. Schauer, Sangeeta R. Shikora. Guerbali, C. GI Peptides, Energy Balance, and Cancer. (2015) Bariatric and metabolic surgery. 2016. H Barnett, A. Surgery for Obesity and Related Diseases 12:3, 606-612. Betancourt-Garcia, Armando Arguelles, Jorge Montes, Ambrosio Hernandez, Manish Singh, R. (2016) Mid-Term Remission of Type 2 Diabetes Mellitus After Laparoscopic Roux En-Y Gastric Bypass. The study population had relatively advanced disease, including many patients with major diabetes-related coexisting illnesses or evidence of end-organ damage, including retinopathy in 14 to 22% and nephropathy (microalbuminuria) in 14 to 29% (Table S1 in the Supplementary Appendix ). (2015) Bariatric Surgery can Lead to Net Cost Savings to Health Care Systems: Results from a Comprehensive European Decision Analytic Model. H. Figure 2 Total 24-Hour Urinary Nitrogen Excretion and Changes in Body Weight. Kelley, Liangsu Wang. le Roux. (2016) Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2. Other Health Outcomes Table 2 shows changes in clinical and laboratory outcomes at 12 months. Bhatt, Philip Schauer. CrossRef 40 Wei-Jei Lee, Keong Chong, Shu-Chun Chen, James Zachariah, Kong-Han Ser, Yi-Chih Lee, Jung-Chien Chen. Bariatric surgery vs. Gadiot, Brechtje A. (2016) Weight reduction and improvement in diabetes by the duodenal-jejunal bypass liner: a 198 patient cohort study. Perioperative safety in the Longitudinal Assessment of Bariatric Surgery. (2015) Duodenal-jejunal exclusion improves insulin resistance in type 2 diabetic rats by upregulating the hepatic insulin signaling pathway. Considine. Surgery for Obesity and Related Diseases 12:9, 1725-1730. Primomo, Tanyaradzwa Kajese, Garth Davis, Robert Davis, Shinil Shah, Maddie Orsak, Christina Morrison. Dan, H. CrossRef 194 Maria Grazia Zenti, Ilaria Rubbo, Giulia Ceradini, Elisabetta Rinaldi, Luisa Nadalini, Marco Battistoni, Michele Genna, Enzo Bonora, Giacomo Zoppini. Wright, Nana Gletsu-Miller. Eckel, Philip R. Reeder. Cefalu, Francesco Rubino, David E. Kaplan, Gaspar Taroncher-Oldenburg, David E. Aronne. (2016) Is there a role for enhanced recovery after laparoscopic bariatric surgery. Kapralou, J. (2016) The Contribution of Diabetes Education in the Treatment of People with Type 2 Diabetes and Risk of Cardiovascular Disease. Surgery for Obesity and Related Diseases 11:1, e5-e7. El Hajj Fuleihan. Patients providing written informed consent entered a 12-week screening period and underwent repeated physical and laboratory evaluations to confirm eligibility. (2015) Significant Improvement of Erectile Function after Roux-en-Y Gastric Bypass Surgery in Obese Chinese Men with Erectile Dysfunction. (2016) Longer-Term Physiological and Metabolic Effects of Gastric Bypass Surgery. (2016) Gastrointestinal weight loss surgery for the management of type 2 diabetes: A view from Greece. CrossRef 37 Nicola Basso, Emanuele Soricelli, Lidia Castagneto-Gissey, Giovanni Casella, Davide Albanese, Francesca Fava, Claudio Donati, Kieran Tuohy, Giulia Angelini, Federica La Neve, Anna Severino, Virginia Kamvissi-Lorenz, Andrea L. Cummings. Participants were randomly assigned, in a two-by-two factorial design, to one of five ad libitum diets to prevent weight regain over a 26-week period: a low-protein and low-glycemic-index diet, a low-protein and high-glycemic-index diet, a high-protein and low-glycemic-index diet, a high-protein and high-glycemic-index diet, or a control diet. (2015) Citation Analysis in Bariatric Surgery. Variables with a non-normal distribution are reported as medians and interquartile ranges. CrossRef 277 George Argyropoulos. (2015) Physiological adaptations following Roux-en-Y gastric bypass and the identification of targets for bariatric mimetic pharmacotherapy. Sirlin, Scott B. (2016) Laparoscopic Adjustable Gastric Banding Revisions in Singapore: a 10-Year Experience. CrossRef 124 Yong Yan, Yanhua Sha, Guoxiang Yao, Shiguang Wang, Fanzhi Kong, Haijun Liu, Guangjun Zhang, Haiqing Zhang, Cheng Hu, Xueli Zhang. Saunders, Aku Ude-Welcome, Ann Marie Schmidt, Van Dunn, H. M. le Roux, Hyeon Soo Park, Gon Sup Kim, Jeeyoun Jung, Geum-Sook Hwang, Youn Kyoung Seo, Tae Kyung Ha, Eunyoung Ha. (2016) A low-fat high-carbohydrate diet reduces plasma total adiponectin concentrations compared to a moderate-fat diet with no impact on biomarkers of systemic inflammation in a randomized controlled feeding study. Petry. Chiang, Daniel S. There was no significant heterogeneity among the subgroups stratified according to median age, BMI, use of insulin, or duration of diabetes (Table S5 in the Supplementary Appendix ). CrossRef 257 William H Dietz, Louise A Baur, Kevin Hall, Rebecca M Puhl, Elsie M Taveras, Ricardo Uauy, Peter Kopelman. Goodpaster. (2016) Learning curve for laparoscopic sleeve gastrectomy: role of training in a high-volume bariatric center. Lund, M. Joseph, Sherita Hill Golden. (2016) Metabolic Surgery for Type 2 Diabetes: Changing the Landscape of Diabetes Care. (2016) Metabolic Syndrome After Roux-en-Y Gastric Bypass Surgery in Chinese Obese Patients with Type 2 Diabetes. CrossRef 259 Nasreen Alfaris, Alyssa M Minnick, Christina M Hopkins, Robert I Berkowitz, Thomas A Wadden. (2015) Predictive Factors of Type 2 Diabetes Mellitus Remission Following Bariatric Surgery: a Meta-analysis. Kroh. Kuk. (2016) The Diabetes Surgery Summit II Guidelines: a Disease-Based Clinical Recommendation. (2015) Early postoperative weight loss predicts maximal weight loss after sleeve gastrectomy and Roux-en-Y gastric bypass. Surgery for Obesity and Related Diseases 11:3, 704-710. Varban, Elif A. (2016) Effect of Roux-en-Y gastric bypass on the remission of type 2 diabetes: a 3-year study in Chinese patients with a BMI Surgery for Obesity and Related Diseases 12:7, 1357-1363. Brathwaite, Louis Ragolia. (2016) Targeting the gut to treat obesity and its metabolic comorbidities: focus on bariatric surgery - view from the chair. Mannaerts. CrossRef 256 Ido Mizrahi, Nahum Beglaibter, Natalia Simanovsky, Natali Lioubashevsky, Haggi Mazeh, Muhammad Ghanem, Katya Chapchay, Ahmed Eid, Ronit Grinbaum. (2015) Research Priorities in Bariatric Surgery. Knudson, Charles J. CrossRef 109 Kee Yuan Ngiam, Valerie Yu Hui Khoo, Lucy Kong, Anton Kui Sing Cheng. (2015) The Sleeve Bypass Trial: a multicentre randomized controlled trial comparing the long term outcome of laparoscopic sleeve gastrectomy and gastric bypass for morbid obesity in terms of excess BMI loss percentage and quality of life. Bindels. Jolles, Luke M. (2015) Reproducibility of MR-based liver fat quantification across field strength: Same-day comparison between 1. Berends. Important limitations of our study include the relatively short duration of follow-up (12 months) and the single-center, open-label nature of the study. (2015) The rationale for a duodenal switch as the primary surgical treatment of advanced type 2 diabetes mellitus and metabolic disease. Patients were counseled by a diabetes educator and evaluated for bariatric surgery by a psychologist and encouraged to participate in the Weight Watchers program. Hormonal mechanisms of weight loss and diabetes resolution after bariatric surgery. (2016) Roux-en-Y Gastric Bypass and Vertical Sleeve Gastrectomy: Divergent Pathways to Improved Glucose Homeostasis. Camacho. (2015) Effect of sleeve gastrectomy on type 2 diabetes as an alternative treatment modality to Roux-en-Y gastric bypass: systemic review and meta-analysis. Journal of Trace Elements in Medicine and Biology 31, 167-172. Lester, David Pace, Chris Smith, Darrell Boone, Raleen Murphy. Flum. Methods Study Design The study rationale and nonblinded design have been reported previously. Timothy Garvey, Samuel Klein, F. Kular, Naveen Manchanda, Gurpreet K. Eligar, Anil Kumar Pura Narayanaswamy. (2016) Comment on: Long-term outcomes after Roux-en-Y gastric bypass: 10-13 year data. Lampe, Mario Kratz. Carlin, Justin B. Recruitment strategies included the use of electronic medical records and advertisements in local media. M. CrossRef 201 Vishesh Khanna, Sangeeta R. Surgery for Obesity and Related Diseases 12:3, 719-720. D. (2016) The impact of bariatric surgery on retinopathy in patients with type 2 diabetes: a retrospective cohort study. (2016) The Newfoundland and Labrador Bariatric Surgery Cohort Study: Rational and Study Protocol. (2015) The impact of laparoscopic diverted sleeve gastrectomy with ileal transposition (DSIT) on short term diabetic medication costs. (2016) A comparative study of the metabolic effects of LSG and LRYGB in Chinese diabetes patients with BMI Surgery for Obesity and Related Diseases. e10. CrossRef 155 Michael Fung, Sean Wharton, Alison Macpherson, Jennifer L. Surgery for Obesity and Related Diseases 12:8, 1457-1465. (2015) Body Mass Index and Health Care Utilization in Diabetic and Nondiabetic Individuals. CrossRef 299 Mark A. Geoffrey Chase, Rinki Murphy. (2016) Roux-en-Y Gastric Bypass Versus Medical Treatment for Type 2 Diabetes Mellitus in Obese Patients. (2016) Limitations of the DiaRem Score in Predicting Remission of Diabetes Following Roux-En-Y Gastric Bypass (RYGB) in an ethnically Diverse Population from a Single Institution in the UK. Inge. CrossRef 164 Ricard Corcelles, Christopher R Daigle, Philip R Schauer. For glycemic measures and body weight, a mixed model for repeated measures was used to analyze the change from baseline and least-square means with corresponding standard errors plotted graphically. Steven, P. (2015) Medium-Term Results of Laparoscopic Sleeve Gastrectomy: a Matched Comparison with Gastric Bypass. (2016) Cardiovascular effects of bariatric surgery. (2015) Management of obesity: improvement of health-care training and systems for prevention and care. Rosenthal. Bray, Philip D. The European Commission Food Quality and Safety Priority of the Sixth Framework Programme (the main sponsor of the study) had no role in the design of the study or in the analysis or interpretation of the data. CrossRef 76 M. (2016) The impact of bariatric surgery on estimated glomerular filtration rate in patients with type 2 diabetes: a retrospective cohort study. Schauer, K. (2016) Essential Fatty Acid Plasma Profiles Following Gastric Bypass and Adjusted Gastric Banding Bariatric Surgeries. (2016) Common Limb Length Does Not Influence Weight Loss After Standard Laparoscopic Roux-En-Y Gastric Bypass. (2016) The Surgical Management of Obesity. Grams, W. Results Of the 150 patients, 93% completed 12 months of follow-up. Endocrinology and Metabolism Clinics of North America 45:2, 419-431. (2016) Management of type 2 diabetes: the current situation and key opportunities to improve care in the UK. Journal of the American College of Surgeons 222:2, 166-173. (2016) Life After Bariatric Surgery: Perceptions of Male Patients and Their Intimate Relationships. (2016) Differential Acute Impacts of Sleeve Gastrectomy, Roux-en-Y Gastric Bypass Surgery and Matched Caloric Restriction Diet on Insulin Secretion, Insulin Effectiveness and Non-Esterified Fatty Acid Levels Among Patients with Type 2 Diabetes. CrossRef 12 S. McGraw, Daniel B. CrossRef 183 Jun-Min Cho, Hyun Jung Kim, Emanuele Lo Menzo, Sungsoo Park, Samuel Szomstein, Raul J. Maghrabi, Kathy Wolski, Beth Abood, Angelo Licata, Claire Pothier, Deepak L. Small. Hansen, Niels Vrang. Hansen, C. Smith, Mark Pedersen, Paul Jose, Peter Nau, Isaac Samuel. advanced practice medical management in the treatment of type 2 diabetes mellitus: rationale and design of the Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently trial (STAMPEDE). Surgery for Obesity and Related Diseases 12:10, 1883-1889. Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial. Khunti. (2015) Differences in Weight Loss and Gut Hormones: Rouen-Y Gastric Bypass and Sleeve Gastrectomy Surgery. Dimick. e3. Diamanti-Kandarakis, J. Wierzbicki, Timothy C. Basso, G. S3 in the Supplementary Appendix ). (2015) Use of sleeve-customized self-expandable metal stents for the treatment of staple-line leakage after laparoscopic sleeve gastrectomy. Obstetrics and Gynecology Clinics of North America 42:2, 335-353. (2016) Patient Selection and Surgical Management of High-Risk Patients with Morbid Obesity. (2015) Effects of laparoscopic gastric plication (LGP) in patients with type 2 diabetes, one year follow-up. (2015) Changes in Glucose Metabolism in Vertical Sleeve Gastrectomy. 5T and 3T in obese subjects. Bramis. (2016) Bariatric surgery in managing diabetes mellitus. (2015) Copper, selenium and zinc levels after bariatric surgery in patients recommended to take multivitamin-mineral supplementation. Annals of the New York Academy of Sciences. Bain, M. (2016) Intermittent Vagal Nerve Block for Improvements in Obesity, Cardiovascular Risk Factors, and Glycemic Control in Patients with Type 2 Diabetes Mellitus: 2-Year Results of the VBLOC DM2 Study. All analyses were performed with the use of SAS software, version 9. Ryan. Surgery for Obesity and Related Diseases 12:7, 1329-1336. Seeley, Patrick Tso, Darleen A. Surgery for Obesity and Related Diseases 12:6, 1144-1162. (2016) Metabolic surgery provides remission of pancreatogenic diabetes in a non-obese patient. De La Cruz-Munoz. Appearance and Internal Aging. Camara, T. (2016) Recent advances in the modification of taste and food preferences following bariatric surgery. S. Diabetes Medications During the trial, the average number of diabetes agents per patient per day tended to increase in the medical-therapy group but decreased significantly in the gastric-bypass group and the sleeve-gastrectomy group (P Figure 1C ). Bariatric procedures were performed laparoscopically by a single surgeon with the use of instruments provided by Ethicon Endo-Surgery. Free Full Text 298 Bote G Bruinsma, Korkut Uygun, Martin L Yarmush, Nima Saeidi. (2015) The Obese Brain—Effects of Bariatric Surgery on Energy Balance Neurocircuitry. Helge, E. Pagadala, A. Zechner, Deborah J Clegg. (2015) Bariatric Surgery: Prevalence, Predictors, and Mechanisms of Diabetes Remission. Kashyap. Carr, Neil Jennings, Norbert Schroeder, Shlok Balupuri, Peter K. Additional surgical interventions were required in four patients, including laparoscopic procedures for blood-clot evacuation, assessment of nausea and vomiting, and cholecystectomy after gastric bypass and jejunostomy for feeding access to treat a gastric leak after sleeve gastrectomy. (2015) The effect of bariatric surgery on obesity and its complications. (2016) Surgical cure for type 2 diabetes by foregut or hindgut operations: a myth or reality. Pressler, April Haller, Joyce Sorrell, Fei Wang, Randy J. (2016) Two-Year Outcomes of Vagal Nerve Blocking (vBloc) for the Treatment of Obesity in the ReCharge Trial. Notably, many patients in the surgical groups, particularly those in the gastric-bypass group, achieved glycemic control without the use of diabetes medications ( Table 3 ). CrossRef 81 Philip Omotosho, Alessandro Mor, Prapimporn Chattranukulchai Shantavasinkul, Leonor Corsino, Alfonso Torquati. (2015) Lemon detox diet reduced body fat, insulin resistance, and serum hs-CRP level without hematological changes in overweight Korean women. (2016) Decreased access to bariatric care: an analysis of referral practices to bariatric specialists. Schou. Abu Dayyeh. Sandoval. No other potential conflict of interest relevant to this article was reported. Schauer, Geltrude Mingrone, Sayeed Ikramuddin, Bruce Wolfe. Kaplan, Gaspar Taroncher-Oldenburg, David E. Marshall, Aaron B. The reduction in prevalence of the metabolic syndrome was significantly greater in the two surgical groups than in the medical-therapy group (Table S3 in the Supplementary Appendix ). e1-350. C. Some adverse events occurred in the bariatric-surgery group, including in four patients who required reoperation. CrossRef 3 Debora S. Results Patients During the first year of follow-up, 8 patients withdrew from the study (1 who did not undergo sleeve gastrectomy and 7 in the medical-therapy group who did not have any follow-up visits). (2016) Bariatric versus diabetes surgery after five years of follow up. Aufenacker, Ignace M. M. Michael Wolfe. Billing. CrossRef 196 Wei-Jei Lee, Abdullah Almulaifi, Keong Chong, Shu-Chun Chen, Jun Juin Tsou, Kong-Han Ser, Yi-Chih Lee, Jung-Chien Chen. (2015) Dose response of exercise training following roux-en-Y gastric bypass surgery: A randomized trial. (2015) Synchronous Ventral Hernia Repair in Patients Undergoing Bariatric Surgery. (2016) MANAGEMENT OF ENDOCRINE DISEASE: Metabolic effects of bariatric surgery. Another 2 patients in the medical-therapy group missed follow-up visits at 9 and 12 months, leaving 140 patients (93%) who completed all analyses. Surgery for Obesity and Related Diseases 12:8, 1474-1481. R. (2016) Preoperative Prediction of Type 2 Diabetes Remission After Gastric Bypass Surgery: a Comparison of DiaRem Scores and ABCD Scores. Wulkan, Thomas H. M. CrossRef 15 Nikhil Mirajkar, Srikanth Bellary, Mohamed Ahmed, Rishi Singhal, Markos Daskalakis, Abd A. Zimmet, Stefano Del Prato, Linong Ji, Shaukat M. (2015) Comparison of Reinforcement Techniques Using Suture on Staple-Line in Sleeve Gastrectomy. Batayyah, R. Castagneto-Gissey, A. 2017. Surgery for Obesity and Related Diseases 11:6, 1257-1263. CrossRef 224 Wei-Jei Lee, Eng-Hong Pok, Abdullah Almulaifi, Ju Juin Tsou, Kong-Han Ser, Yi-Chih Lee. Khan, Lindsey Shaw, Wujuan Zhang, Rosa Maria Salazar Gonzalez, Sarah Mowery, Melissa Oehrle, Xueheng Zhao, Todd Jenkins, Kenneth D. Esteban Varela. CrossRef 300 Guo-Feng Wang, Yong-Xin Yan, Ning Xu, Dong Yin, Yuan Hui, Ji-Ping Zhang, Guan-Jun Han, Ning Ma, Yan Wu, Jing-Zi Xu, Tao Yang. L. (2015) Bariatric surgery and bone health. (2015) Ultrasound Evaluation of Visceral and Subcutaneous Fat Reduction in Morbidly Obese Subjects Undergoing Laparoscopic Gastric Banding, Sleeve Gastrectomy, and Roux-en-Y Gastric Bypass: A Prospective Comparison Study. More than 60% of the surgical patients had moderate-to-severe fatty liver disease on the basis of biopsy samples obtained during surgery (Table S1 in the Supplementary Appendix ). (2015) Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association. A significant decrease in triglycerides occurred at 12 months after gastric bypass, but not after sleeve gastrectomy, as compared with medical therapy. (2015) Body mass index and health status in diabetic and non-diabetic individuals. (2015) Bariatric surgery and prevention of cardiovascular events and mortality in morbid obesity: Mechanisms of action and choice of surgery. Mosinski, M. CrossRef 268 Li Kun, Zhang Pin, Di Jianzhong, Han Xiaodong, Yu Haoyong, Bao Yuqian, Zhang Hongwei. The Journal of Minimally Invasive Surgery 18:3, 59-62. Vafiadis. Media in This Article Figure 1 Screening, Randomization, and Follow-up of Study Participants. CrossRef 39 Chih Kun Huang, Chi-Ming Tai, Po-Chih Chang, Kirubakaran Malapan, Ching-Chung Tsai, Kamthorn Yolsuriyanwong. Pories, John R. 2015. Moore, Clinton E. M. E. (2015) Combination phentermine and topiramate extended release in the management of obesity. Smith, Robert Ratner. An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Pender. CrossRef 101 Tae Jung Oh, Hyuk-Joon Lee, Young Min Cho. (2015) Metabolic and bariatric surgery offers benefits to women beyond weight loss. Noria. (2015) Roux-en-Y gastric bypass attenuates the progression of cardiometabolic complications in obese diabetic rats via alteration in gastrointestinal hormones. Citing Articles 1 Toms Augustin, Ann M. Patients were scheduled for follow-up in a 4-year extension study to assess the durability of glycemic control and diabetes-related complications. Endocrinology: Adult and Pediatric, 479-490. Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults, 85-97. 0% or less 12 months after randomization than were patients receiving medical therapy alone. CrossRef 23 Amalia Gastaldelli, Amerigo Iaconelli, Melania Gaggini, Maria Chiara Magnone, Augusto Veneziani, Francesco Rubino, Geltrude Mingrone. Discussion In our study, obese patients with poorly controlled diabetes who underwent either gastric bypass or sleeve gastrectomy combined with medical therapy were significantly more likely to achieve a glycated hemoglobin level of 6. Huang, O. (2016) The impact of laparoscopic sleeve gastrectomy on weight loss and obesity-associated comorbidities: the results of 3 years of follow-up. I. A. (2015) Obesity in HIV-infected patients in France: Prevalence and surgical treatment options. Lutz, Marco Bueter. Wasserman, Naji N. Cavicchioli, C. M. George M. Eckel, Philip R. Anderson, Caroline Apovian, Megan Ruth, Brian Carmine, Donald Hess. (2016) Lipids and bariatric procedures Part 2 of 2: scientific statement from the American Society for Metabolic and Bariatric Surgery (ASMBS), the National Lipid Association (NLA), and Obesity Medicine Association (OMA)1. (2015) Predictors of Long-Term Diabetes Remission After Metabolic Surgery. CrossRef 33 Keong Chong, Sayeed Ikramuddin, Wei-Jei Lee, Charles J. Roslin, Courtney Cripps, Angeliki Peristeri. Tham, Carel W. Hunt. Mortensen, F. CrossRef 72 Xiao Du, Hong-xu Zhou, Si-qin Zhang, Hao-ming Tian, Zong-guang Zhou, Zhong Cheng. CrossRef 286 Carthage Moran, Donal Sheehan, Fergus Shanahan. van Laarhoven, Laser U. Acta Diabetologica 52:5, 937-942. Costagliola, V. Mingrone. (2016) Loop Duodenojejunal Bypass with Sleeve Gastrectomy: Comparative Study with Roux-en-Y Gastric Bypass in Type 2 Diabetic Patients with a BMI Obesity Surgery 26:10, 2291-2301. (2016) Innovative metabolic operations. Laparoscopic Sleeve Gastrectomy. (2015) Predictors of Short-Term Diabetes Remission After Laparoscopic Roux-en-Y Gastric Bypass. (2015) All-Cause and Cause-Specific Mortality Associated with Bariatric Surgery: A Review. Ulas Biter, Ralph P. Abelson, Cheguevera Afaneh, Patrick Dolan, Genevevie Chartrand, Gregory Dakin, Alfons Pomp. CrossRef 170 Mohammad Talebpour, Atieh Talebpour, Gilda Barzin, Reza Shariat Moharari, Mohammad Reza Khajavi. (2016) Effect of bariatric surgery on cardiometabolic risk in elderly patients: A population-based study. CrossRef 66 Maurizio De Luca, Luigi Angrisani, Jacques Himpens, Luca Busetto, Nicola Scopinaro, Rudolf Weiner, Alberto Sartori, Christine Stier, Muffazal Lakdawala, Aparna G. Mulya, H. (2015) Bariatric Surgery for Metabolic Syndrome in Obesity. Ginsburg. (2015) Treatment of Obesity in 2015. Journal of Cardiopulmonary Rehabilitation and Prevention 35:2, 81-92. le Roux. (2015) Bariatric surgery in obese older people. (2015) To what extent are surgery and invasive procedures effective beyond a placebo response. Oral. (2015) Appropriate Timing of Bariatric Surgery in Obese Type 2 Diabetes Patients. Deutz, Denis Fouque, Laurence Genton, Carmen Gil, Berthold Koletzko, Miguel Leon-Sanz, Raanan Shamir, Joelle Singer, Pierre Singer, Nanette Stroebele-Benschop, Anders Thorell, Arved Weimann, Rocco Barazzoni. Gadiot, Edo O. B. (2015) Predictors of Success after Laparoscopic Sleeve Gastrectomy. All patients received intensive medical therapy, including lifestyle counseling, home glucose monitoring, and the most effective pharmacotherapy currently available. Tahrani. Caughey. CrossRef 274 Simon Kin-Hung Wong, Alice Pik-Shan Kong, Andrea On-Yan Luk, Risa Ozaki, Vanessa Wan-Sze Ng, Harold E. CrossRef 38 T. CrossRef 279 Q. Secondary end points, including BMI, body weight, waist circumference, and the HOMA-IR index, also showed more favorable results in the surgical groups than in the medical-therapy group ( Table 2, and Tables S2 and S3 in the Supplementary Appendix ). Surgery for Obesity and Related Diseases 12:6, 1247-1255. CrossRef 231 Wei-Jei Lee, Ming-Hsien Lee, Po-Jui Yu, Jih-Hua Wei, Keong Chong, Shu-Chun Chen, Abdullah Almulaifi, Yi-Chih Lee. Roslin, Michel Gagner, Richie Goriparthi, Brian Mitzman. (2015) Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery. Kristiansen, Elin Rebecka Carlsson, Sten Madsbad. Table 1 Characteristics of the Patients at Baseline. (2015) One year changes in QCT and DXA bone densities following bariatric surgery in a multiethnic Asian cohort. (2016) Gastric Bypass Surgery but not Caloric Restriction Improves Reproductive Function in Obese Mice. Neyrinck, Laure B. Conclusions In obese patients with uncontrolled type 2 diabetes, 12 months of medical therapy plus bariatric surgery achieved glycemic control in significantly more patients than medical therapy alone. Holt, Sara DeMartini, Timothy J. CrossRef 258 Ming Hsien Lee, Wei-Jei Lee, Keong Chong, Jung-Chien Chen, Kong-Han Ser, Yi-Chih Lee, Shu-Chun Chen. (2016) Short-term Effects of Laparoscopic Adjustable Gastric Banding Versus Roux-en-Y Gastric Bypass. Schauer, K. The Cleveland Clinic had received a grant from Sanofi Aventis for the CRESCENDO trial. CrossRef 133 Ricardo Cohen. CrossRef 111 John A Batsis, William R Miranda, Chaithra Prasad, Maria L Collazo-Clavell, Michael G Sarr, Virend K Somers, Francisco Lopez-Jimenez. (2015) The Effect and Predictive Score of Gastric Bypass and Sleeve Gastrectomy on Type 2 Diabetes Mellitus Patients with BMI. Endocrinology: Adult and Pediatric, 468-478. CrossRef 166 Hyun Joon Kang, Hyung Oh Kim, Ha Na Choi, Soo Min Hong, Cheol Hyun Lee, Yu Jin Kim, So Young Park, Suk Chon, Seungjoon Oh, Jeong-taek Woo, Sung Woon Kim, Sang Youl Rhee. CrossRef 47 Julietta Chang, Stacy Brethauer. Roslin, Courtney N. Endocrinology and Metabolism Clinics of North America 45:4, 905-921. Article Activity 272 articles have cited this article Article The importance of the composition of a diet for the prevention and management of obesity is debated. T. (2016) Bile Acid Modifications at the Microbe-Host Interface: Potential for Nutraceutical and Pharmaceutical Interventions in Host Health. Taudorf, J. We report here the results of the 26-week weight-maintenance intervention phase of the study. Hardman. We used the chi-square test to analyze the primary end point and used analysis of variance to analyze continuous laboratory measurements and compare study groups. O. Aasheim, Barry Sampson, Carel W. (2016) Revisiting the Role of BMI in the Guidelines for Bariatric Surgery: Table 1. (2016) Epidemiology of Diabetes—Status of a Pandemic and Issues Around Metabolic Surgery. CrossRef 6 J. Obesity. Willson, Rami Lutfi. CrossRef 275 Samir Malkani. (2016) Effect of Weight Loss, Diet, Exercise, and Bariatric Surgery on Nonalcoholic Fatty Liver Disease. Methods In this randomized, nonblinded, single-center trial, we evaluated the efficacy of intensive medical therapy alone versus medical therapy plus Roux-en-Y gastric bypass or sleeve gastrectomy in 150 obese patients with uncontrolled type 2 diabetes. (2016) Gastrointestinal devices for the treatment of type 2 diabetes. (2016) Excess Weight Loss and Cardiometabolic Parameter Reduction Diminished among Hispanics Undergoing Bariatric Surgery: Outcomes in More than 2,000 Consecutive Hispanic Patients at a Single Institution. Preliminary results from a specialist obesity treatment center. Bruno, M.
